OSF

Developing a Guideline for Reporting Mediation Analyses (AGReMA) in randomized trials and observational studies Social ScienceSSMART

Hopin Lee, James H McAuley, Rob Herbert, Steven Kamper, Nicolas Henschke, and Christopher M Williams

Investigating causal mechanisms using mediation analysis is becoming increasingly common in psychology, public health, and social science. Despite increasing popularity, the accuracy and completeness when reporting mediation analyses are inconsistent. Inadequate and inaccurate reporting of research stifles replication, limits assessment of potential bias, complicates meta-analyses, and wastes resources. There is a pressing need to develop a reporting standard for mediation analyses. Up to now, there have been no registered initiatives on the “Enhancing the QUAlity and Transparency of health Research” (EQUATOR) network that guide the reporting of mediation analyses. Our proposed project aims to improve the reporting quality of future mediation analyses by developing a reporting guideline through a program of established methodologies (Systematic Review, Delphi Survey, Consensus Meetings, and Guideline Dissemination). The development and implementation of this guideline will improve the transparency of research findings on causal mechanisms across multiple disciplines.

Working Paper: https://osf.io/g7s9s/